Autophagy-mediated degradation of nuclear envelope proteins during oncogene-induced senescence
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چکیده
منابع مشابه
Autophagy-mediated degradation of nuclear envelope proteins during oncogene-induced senescence.
Cellular senescence is a largely irreversible form of cell cycle arrest triggered by various types of damage and stress, including oncogene expression (termed oncogene-induced senescence or OIS). We and others have previously demonstrated that OIS occurs in human benign lesions, acting as a potent tumor suppressor mechanism. Numerous phenotypic changes occur during OIS, both in the cytoplasm an...
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ژورنال
عنوان ژورنال: Carcinogenesis
سال: 2015
ISSN: 0143-3334,1460-2180
DOI: 10.1093/carcin/bgv124